Antimicrobial Resistance

Antimicrobial resistance (AMR) is the ability of a microorganism (e.g. bacteria, viruses, and some parasites) to stop an antimicrobial (e.g. antibiotics, antivirals, and antimalarials) from working against it. As a result, standard treatments become ineffective and infections persist, possibly spreading to others. The Chest Infections NetWork has provided resources and information on AMR.

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  1. WHO Publishes List of Bacteria for Which New Antibiotics Are Urgently Needed
  2. The World Health Organization (WHO) recently published their first-ever list of the most harmful antibiotic-resistant bacterial pathogens. This list is intended to be a warning to governments, scientists, and industry leaders for critical need of additional research and development of novel antimicrobial agents.
  3. Pan-resistant New Delhi Metallo-Beta-Lactamase-Producing Klebsiella pneumoniae
  4. We Will Miss Antibiotics When They're Gone.
  5. Drug-Resistant Superbug May Be Craftier, More Widespread
  6. This study highlights a family of superbugs, known as carbapenem-resistant Enterobacteriaceae, or CRE, which may be spreading more widely than previously thought.
  7. Antimicrobial Resistance:What You Need to Know
  8. NBC News strongly urges for people not to use antibiotics when they do not need them.
  9. Vital Signs: Preventing Antibiotic-Resistant Infections in Hospitals
  10. This report combines national data on antibiotic-resistant bacterial threats with progress on hospital-acquired infection prevention. It is published by the CDC. It highlights some of the increasingly common multidrug resistant bacteria we encounter in the hospital.
  11. Microbiology and Drug Resistance Mechanisms of Fully Resistant Pathogens
  12. This article focuses on bacteria where pan resistance has been or will likely be an issue in the future. These bacteria are being encountered with increasing frequency in the hospital.
  13. Antibiotics for Ventilator-Associated Pneumonia
  14. A meta-analysis of antibiotic treatment of VAP. It does not deal with antibiotic resistance specifically but does deal with monotherapy and dual therapy concern.
  15. Antibiotic De-escalation for Bloodstream Infections and Pneumonia: Systematic Review and Meta-analysis.
  16. This article details de-escalation of antibiotics, which is very important. None of these articles speak directly but only indirectly to antibiotic choices in an era of use of antibiotics with/without resistance.
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