Clarity and integrity of process is paramount in the introduction of new science and it's beneficial application. Disinformation ties a yellow ribbon around every tree obscuring the gold for society in scientific progress.
It is easy to hashtag a label on social media and plug a product with little or no science behind it.
It is also important for us to realize, as tweeted by Margaret Atwood, that all publishing, even via easy-on social media, still bears the accountabilty and liability of any published work.
seeks specifically to identify effective therapeutic application of Telomere Science as represented by 2009 Nobel Prize Laureates, Elizabeth Blackburn, Carol Greider Jack Szostak as well as other leading academics and telomere scientists like Bill Andrews, Maria Blasco, Jerry Shay, Calvin Harley and Sandy Chang. Leading practitioners of therapeutic application we follow include Gabriel Cousins and Ed Park. Bill Andrews and Noel Patton belong to a category of courageous and groundbreaking entrepreneurs seeking to link the best of responsible science with its earliest effective and safe therapeutic application.
The complex matter of early telomere testing procedures, due a separate blog, represents a nascent field of entrants where even the most advanced laboratories are challenged to replicate consistent readings from the same samples. The lower cost less specific labs find themselve marketing a service for determining average telomere length that is increasingly marginalized by the evolving science as insignificant to individual health diagnosis because effective treatment is measured by a reduction of short telomere clusters not average length of a body's general cellular telomere population numbering several quadrillion in the adult human.
A significant challenge to realizing human life extension for Telomere Science is that it serves little purpose for government or vested interests and therefore lacks official funding. It also threatens to revolutionize and simplify general health care which thrives on complexity and is a valued growth industry that seeks to perpetuate itself on symptomatic treatment rather than health breakthrough.
It is the intent of writings like this and in stimulating a crowdsourced dialogue to keep distilling the status of this ongoing science, to clarify the science and formulation honesty of products and to highlight the effectiveness of services to the benefit of those seeking health and not just treatment.
This particular Twitter discussion revolves around Sisel Safe, one of the more prolific users of the twitter hastagged and . There seems to be more enthusiasm than scientific substance offered for this product. We would be pleased to have a response from the company itself or one of the 15 company scientists alluded to yesterday in a now deleted tweet.
Some background on this discussion includes:
1. Among more than 16,000 peer reviewed articles on telomeres and health it is generally agreed that all healthy lifestyle choices including even moods, exercise or responsible nutrition can minimize the progressive annual shortening of telomeres of a minimum of 50 to 100 base pairs. Therefore any healthy product can claim to be telomere supportive.
2. Follow up studies on nutraceuticals that can lengthen telomeres are underway but are both time consuming and expensive. Currently products that contains proven telomere lengthening antigens in vitro lack the back up studies and may label iself as telomere support even though there is reasonable expectation of induced telomere growth in vivo.
3. The following Twitter exchange refers to the astragalus herb ingredient which is a proven Telomerase activator at 6% HeLa, HeLa being what it takes for full activation of cell immortality. Specifically it is the TA-60 and 65 phytochemicals in the herb root that was identified by the University of Hong Kong as the activator and not the root itself. Noel Patton's company states that it takes over 1000 pounds of astragalus root to harvest enough TA-65 for single person's annual dose. Thus the high prices. It is possible to achieve better prices by adding only the root to a Telomere support product. Sissel Safe however claims that "TS-X is the most powerful anti-aging and longevity support product ever." at a fraction of the the TA-65 price. That seems unlikely particularly when they seem reluctant to share the science behind their claims.
4. Bill Andrews who discovered the human telomerase gene in 1994 and provided the scientific platform for subsequent telomerase activation research, helped spearhead the initial launch and test of Noel Patton's TA-65 in 2007. He has since launched ProductB nutraceutical including 15 proven telomerase activators but containing no astragalus phytochemicals. In his A4M address in December 2013 at Las Vegas he said there were three products on the market today that his laboratory has verified to activate telomerase production in the cell and stimulate telomere relengthening. Since Bill already disclosed Product B and TA-65 as proven activators this article asks the question if Sissel Safe is the third proven product.
We welcome your feedback.