- Erika Check Hayden did a great job reporting on this story for Nature News, including a wide range of reactions.
Overwriting DNA: geneticists find thousands of DNA/RNA mismatches, challenging central dogma bit.ly/ijeWvd- As per usual, a lot of quotes got cut from the final piece, but this is the Internet, and Hayden just tweeted the cutting room flloor material.
@leonidkruglyak @girlscientist @Erika_Check @dgmacarthur Curious how big was the 'most scientists contacted' but not quoted group.- @obahcall @leonidkruglyak @girlscientist @dgmacarthur a lot, for this story. "a big deal if it's true" was the consensus.
- for posterity: @leonidkruglyak on DNA/RNA mismatches: "authors have clearly taken considerable care to rule out simple artifacts..."
- "impossible to rule out more subtle issues without looking at the raw data and repeating all the analyses..." (more from @leonidkruglyak...)
- ..."but this should be quickly sorted out once ... many groups attempt to replicate it." 3 of 3 from @leonidkruglyak on http://bit.ly/ijeWvd
- Some other reactions on Twitter:
DUDE, THEY BROKE BIOLOGY! MT @Erika_Check Thousands of DNA/RNA mismatches challenge central dogma http://bit.ly/ijeWvd v @bmahersciwriterBut it looks like there's some backlash afoot.
@girlscientist As in, much more than the (rather genteel) caution expressed in the media coverage so far.
@dgmacarthur I am all ears to see how critics explain mass spec showing proteins match RNA not DNA. That's not an RNAseq problem.- @leonidkruglyak I agree! Break out popcorn! & It was fun to throw caution to winds. How often will one say "textbook-rewriting" for real?
edyong209
Ed Yong
Science writer, creator of Not Exactly Rocket Science, freelance journalist, sci-comms @ Cancer Research UK. Opinions are my own. Obviously.
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